Get to know the science.
Here's our catalog of published research showing the benefits of our ingredients.*
CURCUMIN
Dogs suffering with athritis showed less inflammatory gene expression after being given Curcumin.
Study:
Transcriptome modification of white blood cells after dietary administration of curcumin and non-steroidal anti-inflammatory drug in osteoarthritic affected dogs.
Auddy, B. et al (2008). Journal of American Nutraceutical Association, 11, pp. 50-56
Green-lipped mussel
Dogs taking Green-Lipped Mussel showed improvements in joint pain and swelling.
Study:
Improvement of arthritic signs in dogs fed green-lipped mussel (Perna canaliculus)
Tiffany Linn Bierer and Linh M. Bui. The Journal of nutrition 132 6 Suppl 2 (2002): 1634S-6S .
MSM
Patients with knee Osteoarthritis showed an improvement in pain and physical function after taking MSM for 12 weeks.
Study:
Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study
Debbi, E.M., et al (2011). BMC Complement Altern Med 11, 50.
HYALURONIC ACID
Significant* improvement of knee pain and discomfort in humans.
Study:
The effect of a supplement on knee pain and discomfort evaluated by visual analogue scale (VAS): a randomized, double-blind, placebo-controlled study.
Hatayama, T., et al (2008) Kenkoshien, 10, pp.13-7.
GLUCOSAMINE & CHONDROITIN
Dogs taking Chondroitin & Glucosamine had significant improvements in pain scores.
Study:
Randomised double-blind, positive-controlled trial to assess the efficacy of glucosamine/chondroitin sulfate for the treatment of dogs with osteoarthritis
Mccarthy, G et al. Veterinary journal 174 1 (2007): 54-61 .
VITAMIN
Vitamin C (as calcium ascorbate) reduced joint pain significantly* compared to placebo in humans.
Study:
[Reduced pain from osteoarthritis in hip joint or knee joint during treatment with calcium ascorbate. A randomized, placebo-controlled cross-over trial in general practice]
Jensen NH. Ugeskrift for Laeger. 2003 Jun;165(25):2563-2566.
MANGANESE
Manganese increased both bone mineral density and bone formation.
Study:
Manganese supplementation improves mineral density of the spine and femur and serum osteocalcin in rats.
Bae, YJ., Kim, MH. Biol Trace Elem Res 124, 28–34 (2008).
*We do not claim to treat, cure, allieve, or prevent any disease or illness. Conclusions reached in the above studies are observations of independent researchers and not as a claim made by us.
